Cancer patients can exhibit both that are either
disease-specific or disease non-specific. Disease-specific symptoms
relate to one specific disease and can be used as clues in diagnosis.
The symptoms are mostly caused by the compression upon organs due
to the overly growth of the tumors. Some of the generalized symptoms
occur when substances produced during the growth of tumors enter
into the blood circulation. For example, the steroid-like excretions
into the body of lung cancer patients may affect the calcium level
within the blood, resulting in neural and muscular malfunctions,
causing fatigue and dizziness.
1. Non-disease-specific symptoms
- Weight Loss: Occurs in most patients
- Fever: Occurs in almost every type of tumors. It is sometimes
due to infections with an weakened immune system during cancer
therapies.
- Fatigue: attributed to multiple factors, including physiological,
psychological and environmental, etc. Most patients have fevers.
- Pain: Mainly due to compression from the tumor.
- Discoloration of the skin: deepened complexion, pigmentation,
reddening, rashes, itches, and hair-overgrowth.
2. Disease-specific symptoms
American Cancer Society summarized the following symptoms as valuable
indications for the diagnosis of specific cancers.
- Bowel movement and changes in urination pattern: chronic constipation,
diarrhea, changes in stool shape may indicate colon cancer. Dysuria,
bloody urine and malfunction of bladder may indicate tumors in
bladder or prostate.
- Intractable pain: persistent oral pain may indicate oral cancer.
- Unusual hemorrhage and excretion: Blood in sputum can be a symptom
of lung cancer. Occult blood in defecate indicates colorectal
cancer. Endometrium or cervical hemorrhage may indicate endometrial
cancer. Bloody urine is a symptom of bladder or kidney cancer.
Bloody excretion of nipples may indicates breast cancer.
- Lumps in breast or other locations: Tumors in breasts, testicles,
lymph nodes and other soft tissues often present as mass or lumps
noticeable by touch.
- Indigestion and dysphagia: These symptoms indicate stomach cancer,
esophageal cancer and nasopharyngeal cancer.
- Warts or distinct change in birth mark, etc.: If these skin
marks show signs of discoloration, blurring margin, or significant
enlargement, malignancies such as melanoma may exist.
- Persistent coughs and hoarseness: intractable coughs may be
symptoms of lung cancer, as hoarseness may be the symptom of pharyngeal
or thyroid cancer. Often times, appearance of such symptoms indicates
cancers at late stages.
Different presentations of benign and malignant tumors
| |
Benign Tumors |
Malignant Tumors |
| Local symptoms |
Slow growth, smooth surface, clear margin, movable
by touch, symptoms related to compression. |
Fast growth, expansion in a short period of time, uneven surface,
unclear margin. Other than obstruction and compression, the
tumor affects functions of the organ and creates necrotic ulcer,
which leads to infections (e.g. acute hemotysis in stomach patients) |
| Generalized symptoms |
Normally, no generalized symptom, except for
tumors in the endocrine system. Not life-threatening except
those in vital organs such as the brain |
Generalized symptoms present. Weight loss, fever and loss
of appetite appear in early stages. Late stage patient has anemia
and is often under a state called cahexia, which often causes
death if not treated in time |
3. Other presentations
- Paraneoplastic syndrome:Paraneoplastic syndrome is
a group of symptoms caused by biologically active excretions
secreted by tumorous tissues. These symptoms include: itches,
dermatitis, pulmonary oriented osteohypertrophy, peripheral
neuritis, migratory thrombosis venous infection, glucocorticoid
hyperplasia, chronic anemia, leukmoid reactions, etc.
- Cahexia: Cahexia is characterized by anorexia, malnutrition,
anemia, electrolyte disturbance, decrease in blood protein and
signs of weakness, which may cause distortion of human internal
metabolism and death.
Therefore, early detection of disease-specific symptoms in early-stage
cancers is extremely crucial that early diagnosis and early treatment
may contribute to a better prognosis.
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